Adjudication cloud over West Bengal election candidatesThe ruling TMC has already announced the names of 291 candidates for the 294 assembly seats in the state. Published on: Mar 21, 2026 7:35 AM IST By Joydeep Thakur Share via Copy link Kalita Majhi, 38
Air India flies ‘wrong’ Boeing 777 jet to Vancouver, plane makes U-turn after 4 hoursAccording to Flightradar24, the flight turned back while flying over Chinese airspace after being airborne for roughly four hours. Published on: Mar 21, 2026 7:35 AM IST By HT Correspondent Share via Copy link
The probability of a US recession by the end of 2026 has surged to 36%, according to the prediction platform Polymarket, which tracks real-world events through crowd-sourced betting markets. Polymarket, the world’s largest prediction market, allows traders to buy and sell shares on real-world
I have been asked this, in one form or another, more times than I can count. Sometimes it arrives wrapped in curiosity – a raised eyebrow from a guest who has just noticed my accent, my name, the fact that I come from somewhere else entirely. Sometimes it arrives as a pointed observation
The ongoing geopolitical tensions in the Gulf region due to escalations by Iran, Israel, US could send a ripple effect in the Indian property market. New Delhi: The ongoing geopolitical tensions in the Gulf region due to escalations by Iran, Israel
Love Horoscope Today for March 21, 2026: Today's cosmic shift's impact on your love lifeLove Horoscope Today, March 21, 2026: Find daily astrological predictions for all sun signs. Published on: Mar 21, 2026 6:11 AM IST By Neeraj Dhankher Share via Copy link Our astrologer, Neeraj Dhankher
A Patiala-based photography and cinematography service has won hearts online with a beautifully crafted pre-wedding video that blends vintage storytelling with modern filmmaking. Shubhdeep Films, a Patiala-based photography and cinematography firm
With energy prices still high due to the conflict in the Gulf, governments around the world are being urged to reduce driving speed limits and encourage more working from home. The International Energy Agency (IEA) has suggested ten measures to reduce the amount of energy being consumed across the
Study finds distinct blood markers for early detection of gallbladder cancer
Study finds distinct blood markers for early detection of gallbladder cancer
GUWAHATI
A team of scientists led by researchers from Assam's Tezpur University has identified distinct chemical signatures in blood, offering fresh hope in the early detection of one of the deadliest and often undetected cancers in India.
The scientists who studied patients from Assam, a part of the Northeastern region with one of the highest rates of gallbladder cancer (GBC), found that simple blood tests may one day help doctors identify the cancer much earlier than is currently possible.
Assistant professor Pankaj Barah and research scholar Cinmoyee Baruah of Tezpur University's Department of Molecular Biology and Biotechnology are the lead authors of the study published in the latest issue of the Journal of Proteome Research of the American Chemical Society.
The other members of the interdisciplinary team are Amit Rai of Carl R. Woese Institute for Genomic Biology, the U.S.; Anupam Sarma of Bhubaneswar Barooah Cancer Institute, Guwahati; Gayatri Gogoi, Uttam Konwar, and Utpal Dutta of Assam Medical College and Hospital, Dibrugarh; Subhash Khanna of Swagat Super Speciality and Surgical Hospital, Guwahati; and Sheelendra P. Singh of CSIR–Indian Institute of Toxicology Research, Lucknow.
GBC, a rare but highly aggressive malignancy, is the sixth-most common hepatobiliary cancer, with high mortality rates and a five-year survival of less than 10%. It shows unusual geographical heterogeneity, with the highest incidences from three countries in South America and four in Asia, including India and Japan.
According to the study, GBC is a leading cause of death in these regions, affecting females twice as much as males. It is the third-most common cancer in Northeastern India.
Although gallstone disease is common, only about one in every hundred patients goes on to develop gallbladder cancer. Yet, nearly 90% of cancer patients have a history of gallstones, long confusing doctors.
The disease is notorious for its silent progression, and most patients are diagnosed after the disease has spread. The situation is made worse because its symptoms often resemble common gallstone problems, such as stomach pain or indigestion.
In the study, the researchers compared blood samples from three groups of people: those with gallbladder cancer without stones, those with cancer along with gallstones, and those who had gallstones but no cancer. They aimed to find chemical ‘fingerprints' in the blood that could clearly tell these groups apart.
“Our findings show that changes in metabolites can clearly distinguish gallbladder cancer cases with and without gallstones. This raises the possibility of developing simple blood-based tests that could help in earlier detection,” Dr. Barah said.
“By linking tissue pathology with blood metabolomics, this research bridges the gap between laboratory discoveries and clinical diagnosis,” Dr. Gogoi, a pathologist, said.
The researchers found that certain natural substances linked to bile, digestion, and energy use were present in much higher amounts in cancer patients than in those with gallstones alone. Bile helps digest food, but when its balance is disturbed over a long period, it can damage the gallbladder lining and possibly trigger cancer.
The study also found changes in substances related to protein breakdown and sugar use, suggesting that cancer cells rewire the body's normal processes to fuel their growth. Importantly, some of these changes were common to all gallbladder cancer patients, while others were unique to those who also had gallstones.
“This means gallbladder cancer with stones and without stones may look similar under a microscope, but they behave differently inside the body,” the study noted.
The most significant promise of the study is in improving diagnosis. “The identification of blood-based metabolic markers provides a practical pathway towards early diagnosis and informed clinical decision-making,” Dr. Khanna, a gastrointestinal surgeon, said.
Several blood markers identified by the team were able to distinguish cancer patients from gallstone patients with very high accuracy. To put it simply, these markers worked almost like warning lights, switching on when cancer was present.
The researchers said that this approach, if confirmed in larger studies, could help doctors identify gallstone patients who are at high risk of developing cancer, long before symptoms become severe.
That could make timely surgery possible and save lives, they believed.
Published - January 09, 2026 07:13 pm IST
Source: TheHindu
Related Posts: OpenAI launches Prism for scientists and researchers Nagaland University researchers develop flexible supercapacitor for wearables Punjab University Or ‘Thar University’ Assam scientists probe Sun to rethink gravity Top AI researchers leave OpenAI Meta halts AI division hiring after adding 50+ researchers Researchers unveil breakthrough blood test to detect Researchers identify key genetic factors causing oral cancer early among Indian tobacco chewers Tech researchers sue US Trump administration over visa bans Names proposed by Kerala-based researchers approved for Martian land forms
Ronnie O'Sullivan has set a new record for the highest break in professional snooker history, achieving an astonishing 153 at the World Open in China. This remarkable feat surpasses the previous record of 148 and further solidifies O'Sullivan's status as a legendary figure in the sport
1 days ago
TMC releases manifesto for West Bengal elections, promises to widen its social sector schemesOne of the 10 pledges of the manifesto focuses on empowerment of women, with the party promising to enhance financial assistance under the Lakshmir Bhandar Published on: Mar 21
1 days ago
Think your iPhone is secure? This new iOS 18 hack may change thatA new iOS exploit can steal users' private information from their iPhones simply by users visiting an infected website on Safari web browser. Updated on: Mar 20, 2026 7:37 PM IST By Shweta Ganjoo Share via Copy link If you haven’t
1 days ago
On social media a heartwarming video is making people smile for all the right reasons. Amid the viral trend of recreating a popular scene from Falguni Pathak’s Sawan Mein, one woman has stood out in the most unexpected and beautiful way. While many have been recreating the scene with props like
1 days ago
Cristiano Ronaldo set to recover in time for FIFA World Cup as Portugal head coach gives major injury update Updated on: Mar 21, 2026 6:11 AM IST Written by Neelav Chakravarti Share via Copy link Cristiano Ronaldo is currently recovering from an injury
1 days ago
A jury in the federal court in San Francisco has found Elon Musk liable for misleading investors during the period leading up to his $44 billion acquisition of Twitter in 2022. According to the jury, Musk deliberately pushed down the company’s stock price in the months before completing the deal
1 days ago
Joshua Jefferson injury update: Iowa State star could play vs Kentucky, X-ray results revealed Updated on: Mar 21, 2026 4:31 AM IST By Yash Nitish Bajaj Share via Copy link Iowa State Cyclones forward Joshua Jefferson (5) shoots a layup against Tennessee State Tigers forwards Antoine Lorick III
1 days ago
Tributes have been pouring in from around the world to US martial artist and Hollywood action star Chuck Norris, who died aged 86. "He may have a warrior exterior, but his heart was so full of love," his daughter Danilee Norris said. Swedish actor and martial artist Dolph Lundgren - who starred
1 days ago
Monday's air strike on Kabul resulted in the highest number of casualties seen since hostilities began again in February. Within hours of explosions ringing across the capital, both sides were posting on social media - a war of words as people searched for answers
1 days ago
Raymond Group Chairman Gautam Hari Singhania has been injured in a speedboat accident in the Maldives. He was among tourists when the boat capsized. Singhania has been rescued and is recovering in Mumbai. Search operations are underway for two other Indian men who are missing
1 days ago
In 2022, as the number of Covid-19 cases began falling and travel opened up again, 30-year-old Irshit Ali’s life changed. There was a sudden surge of tourists in his hometown of Ladakh, where he worked ferrying tourists in his van. This was good for business.In 2022
1 days ago
Another twist in Formula 1’s ever-shifting management landscape, and this one comes with immediate impact. Jonathan Wheatley has stepped down from his role with Audi with immediate effect, just a year after joining the project. And the timing? Hardly coincidental
1 days ago
Two Congress leaders, B.S. Anoop and R.S. Arun Raj, joined the BJP in Thiruvananthapuram, expressing dissatisfaction with the Congress leadership. Both leaders, denied tickets for the upcoming Assembly elections, are expected to contest from Chirayinkeezhu and Chadayamangalam respectively
1 days ago
Tarot Horoscope Today for March 21, 2026: Here's your tarot message based on your zodiac signThis article will dive into the daily tarot reading for each zodiac sign for March 21, 2026, with our expert's predictions. Published on: Mar 21, 2026 7:03 AM IST By Neeraj Dhankher Share via Copy link The
1 days ago
Washington, Mar 21 (PTI) The United States has announced the temporary lifting of sanctions on the sale of Iranian oil stranded at sea in an effort to cool down soaring global crude prices. US Treasury Secretary Scott Bessent said the temporary measure will make available 140 million barrels of
1 days ago
The Supreme Court has permitted the Brihanmumbai Municipal Corporation to cut more than 45,000 mangroves. This is for the proposed Versova-Bhayandar coastal road project in north Mumbai. The project aims to significantly reduce travel time and distance
1 days ago
Prakash Raj reacts to tweet talking about Allu Arjun, Vijay Deverakonda, Jr NTR, and Mahesh Babu praising Dhurandhar 2Prakash Raj also shared a video of the song Abhi Na Jaao Chhod Kar and wrote that he is very far from Dhurandhar 2. Check his posts here. Mar 21, 2026
1 days ago
Techie earning $85,000 in Canada considers moving to India for ₹26 LPA FAANG job, internet reactsIn a Reddit post, the techie shared that though the Canadian salary looks good on paper, the reality is very different. Published on: Mar 21, 2026 7:45 AM IST By Trisha Sengupta Share via Copy link A
1 days ago
Trent Alexander-Arnold's omission from Thomas Tuchel's largest England squad is the latest blow to his stop-start international career and casts huge doubt on his hopes of playing at the World Cup. Head coach Tuchel said on Friday he had "not yet" spoken to the 27-year-old about his exclusion
1 days ago
Congress leadership has brought peace to Kerala's party affairs. K Sudhakaran will lead the campaign in Kannur. Adoor Prakash has withdrawn his assembly seat claim. The party is optimistic about the upcoming April 9 election. Rahul Gandhi expressed commitment to Kerala's future
1 days ago
Iran’s Foreign Minister Abbas Araqchi on Friday pushed back strongly against US President Donald Trump’s claim that Tehran was preparing to attack American forces, warning of a forceful response if Iran’s infrastructure is hit. “We are men and women of principles
1 days ago
Fans are pouring into the historic heart of South Korea's capital for what may well be the year's biggest event: the return of the world's most successful band in recent years, BTS. Some 260,000 people are expected to turn up on Saturday at Gwanghwamun Square, where the seven K-pop stars - RM, Jin
1 days ago
Elon Musk was misleading in his public statements during a crucial period of his 2022 Twitter takeover, a jury has found. After two days of deliberations, a jury in San Francisco federal court decided in a unanimous verdict against the tech titan
1 days ago
Rishi Kapoor, Ratna Pathak Shah instantly agreed to Kapoor & Sons, says film's director: After being rejected by actors…Shakun Batra was asked about taking creative risks with Kapoor & Sons. He said that at that time, honestly, he didn't care. Mar 21, 2026
1 days ago
Major banks — HDFC Bank, Punjab National Bank (PNB) and Bandhan Bank have announced rule changes related to ATM withdrawals from 1 April 2026. New Delhi: From 1 April 2026 several banks will change rules related to ATM cash withdrawal limits
1 days ago
The BJP in Assam is bringing in leaders from rival parties like AGP and Congress. Many new candidates are former Congress members. This has upset long-time BJP workers. Himanta Biswa Sarma's influence is seen in candidate selection. Senior leaders are addressing concerns from disgruntled party
1 days ago
Bengaluru founder expresses frustration over AI-generated job applications: ‘Too much noise, quality people are less’Raj Vikramaditya, a Bengaluru-based founder of takeUforward, shared his concerns in a post on X. Published on: Mar 21, 2026 7:47 AM IST By Sakshi Sah Share via Copy link Hiring
1 days ago
